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Prospective Evaluation of Open-angle Glaucoma Subjects on Two Topical Hypotensive Medication Treated With Two iStents

Phase 4
Completed
Conditions
Subjects With Primary Open-angle Glaucoma (POAG)
Interventions
Device: iStents
Registration Number
NCT01252888
Lead Sponsor
Glaukos Corporation
Brief Summary

The purpose of this study is to assess efficacy and safety of two iStents for the reduction of intraocular pressure associated with primary open-angle glaucoma.

Detailed Description

This study evaluates the safety and efficacy of two iStents implanted in primary open-angle glaucoma subjects.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
39
Inclusion Criteria
  • Diagnosed with primary open-angle glaucoma (POAG)
  • Subjects on two topical hypotensive medications
Exclusion Criteria
  • Traumatic, uveitic, neovascular, or angle closure glaucoma
  • Fellow eye already enrolled

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Two iStent devices and medicationiStentsImplantation of two iStents through small temporal clear corneal incision
Primary Outcome Measures
NameTimeMethod
mean diurnal IOP reduction of greater than or equal to 20% at Month 12 vs baseline12 months
Secondary Outcome Measures
NameTimeMethod
Mean diurnal IOP < 18 mmHg at month 1212 months

Trial Locations

Locations (1)

S.V. Malayna's Ophthalmology Centre

🇦🇲

Yerevan, Armenia

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