Effect of prophylactic isosorbide mononitrate on the incidence of preeclampsia in high risk women â?? A double blind randomized controlled trial. - NOPE (Nitric Oxide in Prevention of pre-Eclampsia) Trial

Jawaharlal Institute of Post graduate Medical Education and Research0 个研究点目标入组 100 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Women with one high risk factor / two or more moderate risk factors as given below
•High risk factors:
•1. Previous pregnancy with h/o hypertensive disorders (pre-eclampsia, eclampsia, gestational hypertension, chronic hypertension), IUGR, abruption.
•2. Chronic hypertension
•3.Chronic kidney disease
•4. Autoimmune diseases such as SLE, antiphospolipid antibody syndrome.
•Moderate risk factors:
•1.First pregnancy
•2.Pregnancy interval > 10 years
•3.BMI >35/m2 at first visit
•4.Age >40 years
•5.Family h/o Pre eclampsia.

•1. Women with h/o heart disease (congenital heart disease, valvular heart disease, ischemic heart disease)
•2. Women with Hb < 8 g/dl
•3. Multi-fetal gestations
•4. Diabetes, Chronic Renal/Liver disease, Epilepsy
•5. Women with history of allergy to ISMN

发起方

Jawaharlal Institute of Post graduate Medical Education and Research