NCT01231152Unknown不适用
The Relation of Obesity With Metabolic Disorders, Inflammation Markers and Arterial Blood Pressure With Preclinical Target-organ Damage in Children and Young Adolescents.
University of Athens1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2010年9月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Blood Pressure levels, Target organ damage (Left Ventricular Hypertrophy, IMT, pulse wave velocity, microalbuminuria), Insulin Resistance
研究概览
简要总结
The aim of the study is to investigate the association of obesity with arterial blood pressure, atherosclerosis, target organ damage (heart, arteries, kidney) and insulin resistance in children and young adolescents.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 8 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Overweight (85th<BMI<95th percentile) and obese (BMI>=95th percentile) children and adolescents
- •No medication treatment (apart from bronchodilators, T4 in euthyroid children)
- •No severe mental problem
- •Parents' and patients' signed consent
排除标准
- •Severe chronic or acute cardiac disease or other severe chronic or acute disease
- •Any acute inflammation
- •Familial dyslipidemia
- •Clinical hypothyroidism or other endocrinopathy
- •Poor compliance.
结局指标
主要结局
Blood Pressure levels, Target organ damage (Left Ventricular Hypertrophy, IMT, pulse wave velocity, microalbuminuria), Insulin Resistance
时间窗: 3 weeks
次要结局
未报告次要终点
研究者
George S. Stergiou
Associate Professor of Medicine and Hypertension
University of Athens
研究点 (1)
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