The Impact of Obesity on Children and Adolescents.

• Conditions: Obesity; Cardiovascular Risk Factors

• Registration Number: NCT01231152
• Lead Sponsor: University of Athens

Brief Summary

The aim of the study is to investigate the association of obesity with arterial blood pressure, atherosclerosis, target organ damage (heart, arteries, kidney) and insulin resistance in children and young adolescents.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-09
• Study First Submitted: 2010-10-29
• Study First Submitted QC: 2010-10-29
• Study First Posted: 2010-11-01
• Status Verified: 2012-05
• Last Update Submitted: 2012-05-24
• Last Update Posted: 2012-05-25
• Primary Completion: 2012-12
• Study Completion: 2012-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Overweight (85th<BMI<95th percentile) and obese (BMI>=95th percentile) children and adolescents
• No medication treatment (apart from bronchodilators, T4 in euthyroid children)
• No severe mental problem
• Parents' and patients' signed consent

Exclusion Criteria

• Severe chronic or acute cardiac disease or other severe chronic or acute disease
• Any acute inflammation
• Familial dyslipidemia
• Clinical hypothyroidism or other endocrinopathy
• Poor compliance.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood Pressure levels, Target organ damage (Left Ventricular Hypertrophy, IMT, pulse wave velocity, microalbuminuria), Insulin Resistance	3 weeks

Trial Locations

Locations (1)

Hypertension Center, Third Department of Medicine, University of Athens; 🇬🇷 Athens, Greece