Contribution of coagulation and inflammation to the extent of atherosclerosis in patients with peripheral vascular disease
Recruiting
- Conditions
- ENG:- Atherosclerosis- Atherothrombosis- Peripheral artery disease- Peripheral vascular disease- PAD- Cardiovascular diseaseNL- Atherosclerose- Atherothrombose- Perifeer vaatlijden- Hart-en vaatziekten
- Registration Number
- NL-OMON21578
- Lead Sponsor
- Maatricht University
- Brief Summary
ot applicable
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 315
Inclusion Criteria
Patients diagnosed with peripheral artery disease, both new patients and patients currently in follow-up
- Patients who signed declaration of consent
Exclusion Criteria
- Usage of therapeutic doses of anticoagulants (vitamin K antagonists, direct oral anticoagulants, low molecular weight heparins)
- Pregnancy, oral contraceptives, hormone replacement therapy
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber and type of atherothrombotic events: Coronary artery disease, myocardial infarction, stroke, limb ischemia, all-cause and cardiovascular mortality.
- Secondary Outcome Measures
Name Time Method - Differences in coagulation and inflammation profile<br /><br>- Differences in platelet reactivity<br /><br>- Differences in medication adherence rate<br /><br>- Sensitivity and specificity of a newly developed functional assay