Short-Term Executive Functioning Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Change from baseline executive functioning composite score at post-treatment assessment
研究概览
简要总结
Cognitive remediation (CR) therapies refer to a number of recent developments to use behavioural strategies to improve neurocognitive abilities and improve everyday functioning in mental disorders such as schizophrenia, bipolar disorder, and depression. In this study, we aim to examine whether we can observe CR effects on measures of neuroplasticity, cognition, and functioning when using a rigorous control comparison group. We hypothesize that the active group will exhibit improvements in executive functioning composite scores, improved EEG theta-gamma frequency modulation, and increased EEG alpha power compared to the placebo group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosis of a chronic mental disorder (defined herein as bipolar disorder, major depressive disorder, or a schizophrenia-spectrum disorder)
- •between the ages of 18 and 65
- •speak and read fluent English
- •able to use a computer
排除标准
- •active substance abuse or dependence diagnosis
- •sensory or motor issues that would preclude completion of study procedures
- •enrollment in a cognitive remediation program or use of cognitive training programs (e.g. lumosity.com) within the past 6 months
研究组 & 干预措施
Executive Function Training
Two weeks of training of cognitive domain of executive functioning
Using online program (Scientific Brain Training Pro)
Four exercises
干预措施: Executive Function Training (Behavioral)
Placebo Training
Two weeks of training with exercises not affecting working memory, information processing speed, or cognitive load
Exercises maintain other traditional progressive aspects to preserve appearance of dynamic titration of difficulty levels
Using online program (Scientific Brain Training Pro)
Four exercises
干预措施: Placebo (Behavioral)
结局指标
主要结局
Change from baseline executive functioning composite score at post-treatment assessment
时间窗: Pre-training assessment (Week 1) and post-training assessment (Week 4)
Composite score based on four tests of cognition
次要结局
- Change from baseline EEG theta-gamma frequency modulation at post-treatment assessment(Pre-training assessment (Week 1) and post-training assessment (Week 4))
- Change from baseline EEG alpha power at post-treatment assessment(Pre-training assessment (Week 1) and post-training assessment (Week 4))
研究者
Dr. Christopher Bowie
Dr.
Queen's University