Efficacy of Anterior and Middle Superior Alveolar (AMSA) Nerve Block Anesthesia Obtained by Articaine Computer-controlled and Conventional Delivery
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Success of Pulpal Anesthesia for Central Incisive
研究概览
简要总结
The purpose of this study was to investigate and compare pulpal anesthesia and cardiovascular parameters obtained with 0.6 ml of 4% articaine with epinephrine (1:100.000) for anterior and middle superior alveolar nerve (AMSA) block performed by standard and computer-controlled delivery for maxillary teeth extraction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •maxillary incisors canines or premolars indicated for extraction due to periapical pathology, root fracture or orthodontic treatment
排除标准
- •allergies to local anesthetic solution ingredients, food and drugs
- •alcohol and drugs abuse
- •heavy tobacco smoking
研究组 & 干预措施
Computer controlled 4% articaine delivery by Anaeject
干预措施: Computer controlled 4% articaine delivery by Anaeject (Drug)
Conventional 4% articaine delivery by carpule syringe
干预措施: Conventional 4% articaine delivery by carpule syringe (Drug)
结局指标
主要结局
Success of Pulpal Anesthesia for Central Incisive
时间窗: after 1 hour
Measured by pulp sensitivity to electrical pulp tester
Success of Pulpal Anesthesia for First Premolar
时间窗: after 1 hour
Measured by pulp sensitivity to electrical pulp tester
Success of Pulpal Anesthesia for Lateral Incisive
时间窗: after 1 hour
Measured by pulp sensitivity to electrical pulp tester
Success of Pulpal Anesthesia for Canine
时间窗: after 1 hour
Measured by pulp sensitivity to electrical pulp tester
Success of Pulpal Anesthesia for Second Premolar
时间窗: after 1 hour
Measured by pulp sensitivity to electrical pulp tester
次要结局
- Systolic blood pressure at 5th minute(5th minute)
- Systolic blood pressure at 15th minute(15th minute)
- Duration First Premolar(up to 60 minutes)
- Heart rate(baseline)
- Heart rate at 5th minute(5th minute)
- Onset Lateral Incisive(up to 8 minutes)
- Onset First Premolar(up to 8 minutes)
- Duration Canine(up to 60 minutes)
- Onset Canine(up to 8 minutes)
- Onset Central Incisive(up to 8 minutes)
- Duration Central Incisive(up to 60 minutes)
- Onset Second Premolar(up to 8 minutes)
- Duration Lateral Incisive(up to 60 minutes)
- Diastolic blood pressure at 5th minute(5th minute)
- Duration Second Premolar(up to 60 minutes)
- Systolic blood pressure(baseline)
- Systolic blood pressure at 10th minute(10th minute)
- Systolic blood pressure at 30th minute(30th minute)
- Diastolic blood pressure(baseline)
- Diastolic blood pressure at 10th minute(10th minute)
- Diastolic blood pressure at 15th minute(15th minute)
- Diastolic blood pressure at 30th minute(30th minute)
- Heart rate at 10th minute(10th minute)
- Heart rate at 15th minute(15th minute)
- Heart rate at 30th minute(30th minute)
研究者
Bozidar Brkovic, DDS, MSc, PhD, Professor
DDS PhD Professor
University of Belgrade