Comparative evaluation of the effect of calcium hydroxide medicament and low level laser therapy on endotoxin level in Apical periodontitis – An in-vivo study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To assess and compare the effect of calcium hydroxide intra-canal medicament and low level laser therapy and its combinations as final disinfectant on bacterial endotoxin level in apical periodontitis
研究概览
简要总结
This study is a interventional, randomized, parallel group, active controlled trial to assess and compare the effect of calcium hydroxide intra-canal medicament and low level laser therapy and its combination as final disinfectant on bacterial endotoxin level in apical periodontitis that will be conducted in Vokkaligara sangha dental college and hospital, Bangalore, India. The primary outcome measures will be the effect of calcium hydroxide intra-canal medicament and combination of low level laser therapy and calcium hydroxide as final disinfection on bacterial endotoxin level at 14 days and 30 days interval. Also, the effect of low level laser therapy as final disinfectant on bacterial endotoxin level immediately after laser disinfection will be measured.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Single rooted teeth with single canal and pulp necrosis 2.Primary endodontic infection 3.Radiographic evidence of apical periodontitis verified with CBCT.
排除标准
- •1.Teeth which are diagnosed with periodontal problems and with periodontal pocket of more than 4mm 2.Teeth which were previously treated with root canal procedure 3.Patient who received antibiotic in past 3 months and 4.Teeth which cannot be isolated by rubber dam.
结局指标
主要结局
To assess and compare the effect of calcium hydroxide intra-canal medicament and low level laser therapy and its combinations as final disinfectant on bacterial endotoxin level in apical periodontitis
时间窗: 2 time intervals - 14 days and 30 days
次要结局
- The effect of low level laser therapy as final disinfectant on bacterial endotoxin level immediately after laser disinfection will be measured(one time interval)