To compare the ability of 2 treatment modalities on reducing infection of patients requiring root canal treatment on infected teeth

Not yet recruiting

Conditions: Chronic apical periodontitis, (2) ICD-10 Condition: A488||Other specified bacterial diseases,

Registration Number: CTRI/2022/05/042674

Lead Sponsor: Rajiv Gandhi University of Health Sciences

Brief Summary: This study is a interventional, randomized, parallel group, active controlled trial to assess and compare the effect of calcium hydroxide intra-canal medicament and low level laser therapy and its combination as final disinfectant on bacterial endotoxin level in apical periodontitis that will be conducted in Vokkaligara sangha dental college and hospital, Bangalore, India. The primary outcome measures will be the effect of calcium hydroxide intra-canal medicament and combination of low level laser therapy and calcium hydroxide as final disinfection on bacterial endotoxin level at 14 days and 30 days interval. Also, the effect of low level laser therapy as final disinfectant on bacterial endotoxin level immediately after laser disinfection will be measured.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

1.Single rooted teeth with single canal and pulp necrosis 2.Primary endodontic infection 3.Radiographic evidence of apical periodontitis verified with CBCT.

Exclusion Criteria

1.Teeth which are diagnosed with periodontal problems and with periodontal pocket of more than 4mm 2.Teeth which were previously treated with root canal procedure 3.Patient who received antibiotic in past 3 months and 4.Teeth which cannot be isolated by rubber dam.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess and compare the effect of calcium hydroxide intra-canal medicament and low level laser therapy and its combinations as final disinfectant on bacterial endotoxin level in apical periodontitis	2 time intervals - 14 days and 30 days

Secondary Outcome Measures

Name	Time	Method
The effect of low level laser therapy as final disinfectant on bacterial endotoxin level immediately after laser disinfection will be measured	one time interval

Trial Locations

Locations (1): Vokkaligara Sangha Dental College and Hospital
🇮🇳
Bangalore, KARNATAKA, India
Vokkaligara Sangha Dental College and Hospital
🇮🇳Bangalore, KARNATAKA, India
Dr AdarshaMS
Principal investigator
9844474688
adarshsgowda@yahoo.com