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The Safety of a High-Dose, Rapid Infusion of Iron Sucrose

Phase 2
Withdrawn
Conditions
Iron Deficiency
Interventions
Registration Number
NCT02977611
Lead Sponsor
The Guthrie Clinic
Brief Summary

Iron sucrose infusion is an iron replacement used to treat iron deficiency anemia (not enough iron in the body to make hemoglobin). Iron is a mineral that the body needs to produce hemoglobin, which carries oxygen in the blood. When the body does not get enough iron, it cannot produce enough hemoglobin and you become anemic.

The research study is looking at the side effects of using a higher dose and faster rate of iron sucrose infusion than what is used in standard of care. The purpose of this study is to see if infusion with 500 mg of iron sucrose over a one hour time period can be done safely. If this can be done safely, it may reduce the total number of infusions required and the time for each infusion. This may be less costly and less burdensome to patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Any patient requiring iron infusion
Exclusion Criteria
  • Patients will be excluded from enrollment if they are under the age of 18, unable to give signed consent, are pregnant, have end-stage renal disease, are on hemodialysis (HD), or have a history of clinically significant adverse reactions to iron sucrose.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
High Dose, Rapid Infusion Iron SucroseIron sucrosePatients will receive an infusion of 500 mg of iron sucrose over one hour and will be monitored for four hours.
Primary Outcome Measures
NameTimeMethod
incidence of adverse events in the study population attributed to drug administration.4 hours
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Robert Packer Hospital

🇺🇸

Sayre, Pennsylvania, United States

Robert Packer Hospital
🇺🇸Sayre, Pennsylvania, United States
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