To investigate the effect of vitamin K supplementation on markers of bone turnover and bone density in adolescents and adults with cystic fibrosis - Vitamin K supplementation in Cystic Fibrosis

Barts and the London NHS Trust0 个研究点目标入组 40 人开始时间: 2006年9月18日最近更新: 2019年11月25日

适应症

试验速览

暂无简介。

•Patients with a diagnosis of CF (positive sweat test and genotype testing)
•Patients aged over 16 years (post pubertal-stage IV Tanner)
•Patients who are pancreatic insufficient (i.e. with a positive faecal elastase test and requiring pancreatic enzyme supplementation)
•Are the trial subjects under 18? yes
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Patients already taking vitamin K supplementation,
•Patients with abnormally low vitamin D levels (<30 µg)
•Patients on maintenance oral corticosteroids
•Patients with osteopaenia or osteoporosis and taking bisphosphonates
•Patients who are considered to have very sedentary lifestyle or follow a rigorous exercise training programme
•Patients with overt liver disease
•Patients who do not consent to participate
•Patients with a life expectancy of less than 12 months
•Patients who are non-compliant with maintenance therapies

发起方

Barts and the London NHS Trust