Can cachectic cancer patients manage intense resistance training?
Not Applicable
- Conditions
- C25C34Malignant neoplasm of pancreasMalignant neoplasm of bronchus and lung
- Registration Number
- DRKS00023216
- Lead Sponsor
- niklinik Köln, Centrum für Integrierte Onkologie, Klinik I für Innere Medizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting stopped after recruiting started
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
Pancreatic OR lung cancer +cachexia [>5% body weight loss in <6months] + active systemic cancer treatment
Exclusion Criteria
ECOG>2
Diseases impaireing exercise capability, such as:
- heart insufficiency [NYHA III-IV]
- Resperatory insuffiency [partial/global]
- permanent trompopenia CTC IV°
- coagulation disorders
- symptomatic coronary heart disease [stress ECG necessary]
- Heavy art. hypertension
- COPD in stage IV after GOLD
- Uncontrolled epilepsy
- Uncontrolled cerebral metastases
Medical or mental limitations that, in the investigator's judgment, prohibit participation in the trial or limit the ability to consent
Other participation in a exercise study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Feasibility (Recruitment, Dropouts, Adverse Events, Compliance)
- Secondary Outcome Measures
Name Time Method Body composition (BIA), body weight, cachexia progress, cardiopulmonary exercise performance [spiroergometry], strength performance [1RM leg press, 1RM hand grip, 1min sit-to-stand test], ECOG, blood parameter [Albumin, creatinin, CRP, erytrocytes, leukocytes, thrombocytes, Creatinkinase]; patient-related outcomes via questionnaires: quality of life [EORTC-C30]; Fatigue [MFI20], physical acitivity [BSA]; Depression & anxiety [HADS]; cachexia [FAACT].