Obstructive Sleep Apnoea (OSA) in patients with type 2 diabetes and the effect of continuous positive airway pressure (CPAP) treatment on diabetic control, insulin resistance and blood pressure

Completed

• Conditions: OSA and coexisting Type 2 diabetes; Nervous System Diseases; Sleep apnoea

• Registration Number: ISRCTN28644636
• Lead Sponsor: Diabetes UK

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-14
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 40

Inclusion Criteria

1. Age 18-75
2. Type 2 diabetes
3. OSA with more than 10 >4% SaO2 dips per hour on sleep study
4. Epworth Sleepiness Score >9

Exclusion Criteria

1. Unstable diabetes
2. Respiratory failure requiring urgent nocturnal ventilation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HbA1c% change

Secondary Outcome Measures

Name	Time	Method
Insulin resistance measured by euglycaemic clamp and homeostatic model assessment, blood pressure