Effect of radiofrequency burning of compressed nerve root in low back pain patients and study its effect on CSF markers (IL6, IL8)
Not Applicable
- Conditions
- Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.lumbosacral radicular pain with dermatomal pattern of pain distribution
2. Duration of pain > 3 months
3. MRI confirms level and extent of nerve root impingement with disc herniation
Exclusion Criteria
patient refusal
history of previous spine surgery or soine injury
local site infection
pregnancy, breast feeding
severe systemic diseases
other inflammatory neurological conditions, autoimmune diseases
cauda equina syndrome
coagulopathy, on anticoagulants
malignancy
any spinal deformity or fracture or raised intracranial pressure
psychiatric or cognitive illness
alcohol or drug abuse
red flag sign
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess pain relief following Pulsed Radiofrequency of the Dorsal root ganglion by Numerical Rating Scale (NRS) and compare pre-procedure scores with that of post-procedure scores <br/ ><br>Timepoint: at baseline (pre-procedure), 2 weeks, 3 months
- Secondary Outcome Measures
Name Time Method 1. To evaluate Serum IL6 level in lumbar radicular pain patients and compare pre-RFA levels with that of 3 months post-RFA. <br/ ><br>2. To identify correlation between intensity of pain and Serum IL-6 level <br/ ><br>3. To assess the functional status by Modified Oswestry Disability Questionnaire (MODQ at baseline, 2 weeks, 3 months) and compare pre-procedure score with that of post-procedure score. <br/ ><br>4. To assess any adverse effects and the complications due to the procedure <br/ ><br>Timepoint: pre-procedure and 3 months post-procedure