Factors Related to the Progression of Chronic Kidney Disease

• Conditions: Chronic Kidney Disease

• Registration Number: NCT01317173
• Lead Sponsor: Ankara Education and Research Hospital

Brief Summary

Chronic kidney disease is a progressive disorder that has been influenced with many factors. Most of the patients has altered Ca P metabolism and these dis orders are the contributing factors of the disease progression. It has been recently documented that FGF23 and Klotho are the key factors of PTH secretion Ca-P metabolism. This study aimed to evaluate the impact of Klotho and FGF23 on the progression of stage 3-4 chronic kidney disease.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-03
• Status Verified: 2011-01
• Study First Submitted: 2011-03-16
• Study First Submitted QC: 2011-03-16
• Last Update Submitted: 2011-03-16
• Study First Posted: 2011-03-17
• Last Update Posted: 2011-03-17
• Primary Completion: 2011-05
• Study Completion: 2011-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Non-diabetic chronic kidney disease

Exclusion Criteria

• Presence of DM
• Actively using calcium based phosphorus binder of vitamin D

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Progression of kidney disease	continuous measurement of kidney functions 3 monthly for two years or until the outcome reached	Doubling of creatinin, requirement of renal replacement therapy

Secondary Outcome Measures

Name	Time	Method
Evaluation of Ca P metabolism	3 monthly for two years or until the outcome reached	Determination of Ca-P metabolism disorders.

Trial Locations

Locations (1)

Ankara Education and Research Hospital; 🇹🇷 Ankara, Turkey