The comparison of the efficacy of two therapeutic regimens in the treatment of gastroesophageal reflux disease in term neonates.
Not Applicable
Not yet recruiting
- Conditions
- Gastroesophageal Reflux.Gastro-oesophageal reflux disease
- Registration Number
- IRCT20160827029535N10
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Term neonates aged 1–30 days with gastro esophageal reflux disease
Exclusion Criteria
Neonates with any underlying diseases, including anomalies or gastrointestinal obstruction, neurological disorders, sepsis, NEC, etc.
History of using any sedative , relaxant or anticonvulsive medications
History of ventilation therapy.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The comparison of omeprazole with lansoprazole in neonatal GERD. Timepoint: One week and one month after using each drug. Method of measurement: using (I-GERDQ-R) and related scoring.
- Secondary Outcome Measures
Name Time Method The side effects of each drug. Timepoint: After one week and one month of administration. Method of measurement: Clinical manifestations.