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Clinical Trials/NCT03609567
NCT03609567
Completed
Not Applicable

Aromatherapy as Treatment for Nausea and Vomiting of Pregnancy

Albany Medical College1 site in 1 country17 target enrollmentJune 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pregnancy Emesis
Sponsor
Albany Medical College
Enrollment
17
Locations
1
Primary Endpoint
Mean difference in Pregnancy-Unique Quantification of Emesis (PUQE) score
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

A double-blinded randomized controlled trial comparing essential oil aromatherapy versus placebo for treatment of first trimester nausea and vomiting of pregnancy.

Detailed Description

This is a double-blinded randomized controlled trial investigating the utility of essential oils for aromatherapy, compared to placebo, for treatment of nausea and vomiting in the first trimester of pregnancy.

Registry
clinicaltrials.gov
Start Date
June 1, 2017
End Date
March 1, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Pregnancy at \<14 weeks gestation
  • English-speaking
  • Baseline PUQE score \>=6

Exclusion Criteria

  • Non-compliant with prenatal care or study procedures
  • Hyperemesis gravidarum
  • Allergies to perfumes, essential oils or cosmetics
  • Abnormal sense of smell
  • Known acute or chronic GI disease
  • Use of prescription anti-emetics

Outcomes

Primary Outcomes

Mean difference in Pregnancy-Unique Quantification of Emesis (PUQE) score

Time Frame: First trimester of pregnancy

PUQE score is a validated measure of nausea and vomiting in pregnancy. It is a reliable tool used to measure the severity of nausea and vomiting of pregnancy. It is a questionnaire that measures the number of times in 24 hours a patient wretches, vomits, or feels nauseous. The minimum score is 3, and the maximum is 15. Participants will have PUQE scores calculated at baseline (during enrollment in the first trimester of pregnancy, at whatever age they are at), and after one month of aromatherapy use with either essential oils or placebo, with the mean difference from baseline compared as primary outcome. The Time Frame for participation will be from enrollment until the end of the first trimester (13th week of pregnancy), which, depending on gestational age in weeks at enrollment, may be up to 8 weeks.

Study Sites (1)

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