icorice Influences on cortisol/cortisone, electrolytes and blood pressure - LICORICE study

Academisch Medisch Centrum0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•- Willing and able to participate in the study protocol
•- Written informed consent
•- Age 18-60 years
•- Office diastolic blood pressure maximal 90 mmHg and office systolic blood pressure maximal 140 mmHg
•- BMI > 18 or < 35 g/m2
•- No use of medication which affects the primary or secondary outcome measurements such as diuretics, antihypertensive drugs and NSAIDs < six weeks before start of the study
•- Willing to adhere to the study protocol
•- Accessible veins on arm(s) as determined by examination at information meetings

•- Allergy to one of the ingredients of licorice
•- Office blood pressure >140/90 mm
•- Reported alcohol consumption > 28 units/week or recreational drug use
•- Existing cardiovascular diseases
•- Use of medication which affects the primary or secondary outcome measurements such as diuretics, antihypertensive drugs and NSAIDs < six weeks before start of the study
•- Currently on a medically prescribed diet, or slimming diet
•- Potassium <3.5 mmol/l
•- eGFR <60
•- Excessive ingestion of licorice (>200 gr/week) or >3 litre of licorice tea per week
•- Pregnancy

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