The effect of oral Mullein capsules on the treatment of uterine leiomyomas.
- Conditions
- terine leiomyomas.Leiomyoma of uterus -Leiomyoma of uterus, unspecified
- Registration Number
- IRCT2017012827311N2
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 50
Willingness to participate in the study, having a literate and able to answer the questions, women of reproductive age 18-50 years with asymptomatic uterine leiomyomas that confirmed by abdominal ultrasound (at least one leiomyoma largest than 2.5 cm), women with normal menstruation (35-21 days).
Pregnant and lactating women, desire to become pregnant during the next three months, uterine leiomyoma in size more than 12 cm, the size of the uterine leiomyoma equal or more than 20 weeks of gestation, anemia requiring treatment, history of chronic diseases (such as heart disease, thyroid, etc.) and concurrent use of other medications or herbal remedies, history of previous surgery such as myomectomy, use the OCP or other methods of hormone therapy during the last three months, presence of a hormonal IUD, known diseases of the genital tract, Allergy to treatment.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Size of Uterine Liomyoma. Timepoint: before intervention and 2 month after intervention. Method of measurement: Sonography study.;Menstrual bleeding loss. Timepoint: beefore intervention and 4 ,8 weeks after intervention. Method of measurement: Pictorial Blood Loss Assessment Chart (PBAC).
- Secondary Outcome Measures
Name Time Method Haemoglobin. Timepoint: before intervention and 2 months after intervention. Method of measurement: blood exam.;Size of uterine. Timepoint: before intervention and 2 months after intervention. Method of measurement: Sonography study.;Side events. Timepoint: two months after intervention. Method of measurement: Checklist of side events.;Satisfaction with treatment received. Timepoint: two months after intervention. Method of measurement: Checklist of Satisfaction with treatment received.