Partnering to Enhance Emerging Adults' Response to Programs (PEER)
Overview
- Phase
- N/A
- Intervention
- Motivational Interviewing (MI)
- Conditions
- Alcohol Use, Unspecified
- Sponsor
- UConn Health
- Enrollment
- 248
- Locations
- 1
- Primary Endpoint
- Blood oxygen level dependent (BOLD) response synchrony
- Status
- Recruiting
- Last Updated
- 2 months ago
Overview
Brief Summary
The goal of this clinical trial (CT) is to learn more about emerging adults' and their peers. Here, we will see how co-participating with a peer in health program might impact brain and behavior change over time.
Eligible youth will be invited to come in for a "Participation Day," during which they and a peer will independently complete questionnaires. With a peer, they will then complete a short health program, and undergo a brain scan (fMRI) while completing activities. Our study team will reach out to each participant individually again 3, 6, and 12 months later to learn about health behaviors over time.
Investigators
Sarah Feldstein Ewing
Professor
UConn Health
Eligibility Criteria
Inclusion Criteria
- •within the specified age range
- •agree to be contacted for the 3, 6, and 12 month follow ups
- •provide fully informed consent
Exclusion Criteria
- •left-handed
- •evidence of brain injury/illness and/or neurological, neurodevelopmental disorder including psychosis and related medications (e.g., antipsychotics; neuroleptics)
- •loss of consciousness ≥ 2 minutes
- •other fMRI contraindications (e.g., unremovable metal on/in body, pregnant)
Arms & Interventions
Motivational Interviewing (MI)
Intervention: Motivational Interviewing (MI)
Outcomes
Primary Outcomes
Blood oxygen level dependent (BOLD) response synchrony
Time Frame: Baseline
Mean BOLD time series will be obtained for each region of interest (ROI) during peer-directed change talk trials and temporally aligned across dyad participants. Inter-brain synchrony will be quantified using z-transformed GLM β-weights within ROIs between the BOLD time series of dyad members.
BOLD response synchrony association with behavior change (past month alcohol use days)
Time Frame: 12 Months
Pearson correlation coefficients (r) of Primary Outcome #1 (ROI z-scores representing BOLD response synchrony) with individual Timeline Followback (TLFB) past month drinking days at 12 month follow up.
Secondary Outcomes
- BOLD response synchrony association with behavior change (past month alcohol use days)(3 Months)
- BOLD response synchrony association with behavior change (past month alcohol use days)(6 Months)