Effect of Milk and Yogurt Contained Probiotics Lactobacillus rhamnosus SD11 on Mutans Streptococci in children 12-14 years old
Phase 2
- Conditions
- evel of mutans streptococcicaries statusside effectpersistantchildrenprobioticsmutans streptococcicaries status
- Registration Number
- TCTR20170601002
- Lead Sponsor
- PSU (Super Cluster)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
Subjects are 12-14 years old
good general health condition
subjects have dental caries ≤ 2 teeth
Exclusion Criteria
The exclusion criteria were
i systemic diseases related with immunity problem or severe chronic diseases
ii allergy to cows milk, lactose intolerance, severe food allergy
iii systemic antibiotic medication taken within 2 weeks
iv habitual consumption of probiotics and xylitol
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method decrease oral pathogen (persistant and side effect) at the end and 3, 9 months after end of the intervention cariogenicpathogen evaluation, immunity in saliva
- Secondary Outcome Measures
Name Time Method prevention of dental caries at 3, 9 months after end of the intervention assessment of dental status