Effects of Physical Activity Based on the Transtheoretical Model on Patients With Endometrial Cancer Undergoing Fertility-sparing Treatment: a Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endometrium Cancer
- Sponsor
- Peking University People's Hospital
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- Body weight
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
This study evaluated the clinical outcome of exercise management on patients with endometrial cancer treated with fertility preservation, including the effect of complete response rate, complete response time, recurrence rate, recurrence time, etc., and physical composition, to evaluate the effectiveness of physical activity on weight management.
Investigators
Xiaodan Li
associate professor
Peking University People's Hospital
Eligibility Criteria
Inclusion Criteria
- •Participants were patients who met the following predefined eligibility criteria: Ages 20-40; Overweight or obese; The pathological diagnosis was EC (endometrioid, grade I, no myometrium invasion or metastasis). Not pregnant; Be willing to comply with test requirements after being fully informed of all risks and inconveniences associated with the test.
Exclusion Criteria
- •Recurrent or metastatic disease; Currently participating in regular exercise at least 2 days per week; Pregnant at the start of the study; Or unwilling to comply with research requirements. Patients also completed the Physical Activity Readiness Questionnaire (PAR-Q) through a telephone interview. Patients with one or more potential exercise-related safety risks were excluded.
Outcomes
Primary Outcomes
Body weight
Time Frame: Enrollment，four months after the intervention
Body weight measured naked or wearing work clothes of known weight, an electronic weight scale is used to measure
BMI
Time Frame: Enrollment，four months after the intervention
Body mass index is a standard commonly used in the world to measure the degree of body fat and whether it is healthy. The formula is BMI= weight ÷ height\*height
physical activity level
Time Frame: Enrollment，four months after the intervention
Physical activity energy was calculated using the formula of the International Physical Activity Questionnaire. Calculation Manual: Physical activity amount (MEt-minutes /week)= physical activity intensity MET value × physical activity time (minutes)/ day × activity days.
Secondary Outcomes
- triglyceride(Enrollment，four months after the intervention)
- serum total cholesterol(Enrollment，four months after the intervention)
- Waist Hip Ratio(Enrollment，four months after the intervention)