Evaluation of Renal Perfusion With NIRS in Adult Patients Undergoing Laparoscopic Cholecystectomy.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 58
- 试验地点
- 1
- 主要终点
- Evaluation of renal damage caused by pneumoperitoneum with N-GAL by blood test
研究概览
简要总结
The investigators aimed to show the renal damage caused by increased intra-abdominal pressure in laparoscopic surgeries and to investigate whether its reflection on NIRS would be clinically effective.The main question it aims to answer are:
Does pneumoperitoneum cause renal damage?
NRS monitoring will be performed in patients undergoing laparoscopic surgery. Preoperative and postoperative blood tests will be performed at certain hours. N-GAL, urea and creatinine values will be recorded.
详细描述
Renal NIRS monitoring will be performed in patients undergoing laparoscopic cholecystectomy surgery. Age, gender, BMI, ASA scores, hemogblin/hematocrit values, intraoperative hemodynamic parameters, NIRS values, N-GAL (preoperative, 2nd hour and 24th hour), urea/creatinine (preoperative, postoperative 24th hour) values of the patients will be recorded. .
Before the general anesthesia is performed, the renal tissues of the patients will be visualized by ultrasound, the skin-renal cortex distances will be measured, and suitable patients will be included in the study. Basal rSO2 values will be recorded by placing NIRS probes under the 10-11. intercostal space in the bilateral posterior lateral flank region.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who undergoing elective laparoscopic cholecystectomi surgery lasting longer than 60 minutes
- •BMI:18-25
- •skin-renal cortex distance measured less than 4 cm on ultrasound
- •ASA I-III
排除标准
- •patient who did not give consent
- •patient who had renal operation before,
- •infection, abscess, catheter in the perirenal region
- •hemodynamically unstable patients,
- •patients with renal pathology and abnormal kidney function tests,
- •emergency cases
结局指标
主要结局
Evaluation of renal damage caused by pneumoperitoneum with N-GAL by blood test
时间窗: During laparoscopic cholecystectomy operation and within 24 hours postoperative
Taking a blood test to evaluation N-GAL
Evaluation of renal damage caused by pneumoperitoneum with urea/creatinin by blood test
时间窗: During laparoscopic cholecystectomy operation and within 24 hours postoperative
Taking a blood test to evaluation urea/creatinine values
次要结局
未报告次要终点
研究者
Savas Altinsoy
Associate Professor MD
Diskapi Yildirim Beyazit Education and Research Hospital