Vaginal suppository versus oral capsule of vitamin D for vaginal atrophy in postmenopausal women; A randomized controlled trial.
Phase 4
Not yet recruiting
- Conditions
- Vaginal vitamin Dvaginal atrophy in postmenopausal womenvaginal atrophypostmenopausal womenvitamin D
- Registration Number
- TCTR20210224004
- Lead Sponsor
- Faculty of Medicine Khon kaen University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- 72
Inclusion Criteria
Woman with vaginal atrophy age 45 years old or more who had amenorrhea for at least 1 year or underwent bilateral oophorectomy or who had serum FSH more than 40 IU/ml
Exclusion Criteria
1. who had history hormonal replacement therapy or vitamin D3 used for 12 weeks before enrollment
2. who had abnormal vaginal bleeding for 12 weeks before enrollment
3. who had history used any vaginal suppository or vaginal apply for 4 weeks before enrollment
4. who had history of sexual transmitted disease
5. who had abnormal pap smear
6. hypersensitivity to vitamin D
7. liver or renal failure
8. who had high serum phosphate
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the most bothersome symptoms of vaginal atrophy 4 and 8 weeks after intervention severity of symptoms
- Secondary Outcome Measures
Name Time Method vaginal maturation value 4 and 8 weeks after intervention vaginal maturation value,vaginal pH 4 and 8 weeks after intervention vaginal maturation value,satisfactory 8 weeks after intervention rating scale