Comparative evaluation of ultrasound guided Erector Spinae Plane Block versus Modified Pectoral Nerve Block for post operative analgesia and stress response in patients undergoing Modified Radical Mastectomy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Time to request for 1st supplemental analgesic requirement post-operatively
研究概览
简要总结
We are comparing Erector Spinae Plane Block with Modified Pectoral Nerve Block for post operative analgesia and stress response in patients posted for Modified Radical Mastectomy in Lok Nayak Hospital Delhi. A total of 42 patients with 21 patients in each group will be enrolled for the study. Patients will be explained about the study and written informed consent will be taken. A Preoperative blood sample (total of 6ml) will be taken for analyzing serum cortisol, Neutrophil Lymphocyte ratio and Interleukin-6 blood levels. We will be using standard general anesthesia for induction of patients following which USG guided block site will be identified and local anesthetic drug will be administered. Patients will be followed up post operatively for 24 hours during which numerical rating scale for pain, time for first supplemental analgesia and total amount of analgesic consumption will be determined. Another blood sample(total of 6ml) will be taken 6 hours post surgery for analyzing serum cortisol, Neutrophil Lymphocyte ratio and Interleukin-6 blood levels. Overall patient satisfaction score will also be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- Female
入选标准
- •1.18 to 65 years of age 2.American Society of Anesthesiologists Physical Status I or II.
排除标准
- •1.History of Neuropsychiatric Disorders 2.Infection at local site 3.Coagulopathies and Thrombocytopenia(platelet count less than 1 lacs) 4.BMI more than 30kg/m2 5.On chronic treatment with opioids 6.Pregnancy.
结局指标
主要结局
Time to request for 1st supplemental analgesic requirement post-operatively
时间窗: In postoperative period at 0 minutes,30 minutes,2 hours,4 hours,6 hours,12 hours and 24 hours
次要结局
- 1.Hemodynamic changes(Heart Rate and Mean Arterial Pressure)will be monitored and recorded before induction(baseline),after induction, post block, at skin incision and for every 15 minutes intra-operatively(2.Post-operative NRS score till 24 hours)
研究者
Dr Avnika Laller
Maulana Azad Medical College and associated Lok Nayak Hospital