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Clinical Trials/CTRI/2025/09/093962
CTRI/2025/09/093962
Not yet recruiting
Not Applicable

Effectiveness of closed kinetic chain exercises verses open kinetic chain exercise on reducing pain, improving functional activity and muscle strength in patients with unilateral patellofemoral pain syndrome - comparative study

Lavanya M1 site in 1 country30 target enrollmentStarted: September 10, 2025Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
Lavanya M
Enrollment
30
Locations
1
Primary Endpoint
1.VISUAL ANALOGUE SCALE

Overview

Brief Summary

Patellofemoral pain syndrome (PFPS) is a prevalent musculoskeletal condition characterized by anterior knee pain, particularly during weightbearing

activities. Rehabilitation strategies often incorporate both open kinetic chain (OKC) and closed kinetic chain (CKC) exercises to address pain, improve function, and

enhance muscle strength. However, the comparative effectiveness of these two approaches remains underexplored in patients with unilateral PFPS. Study

aims to compare the effects of CKC exercises versus OKC exercises on pain reduction, functional activity, and quadriceps muscle strength in individuals

with unilateral PFPS. A randomized controlled trial was conducted with 30 participants diagnosed with unilateral PFPS. Participants were randomly assigned

to either the CKC exercise group or the OKC exercise group for a 6-month intervention program. Outcome measures included pain assessment using the

(VAS), functional activity evaluated with the Lysholm knee scoring scale, and strength measured with a handheld dynamometer. Assessments

were performed at baseline and post-intervention

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
20.00 Year(s) to 40.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Normal BMI, Mild to moderate (3-5) Visual Analogue Scale (VAS) score without medication, Lysholm knee scoring (grade- 65 to 83 points fair knee function), Positive Waldron’s test and Patellofemoral Apprehension test, Unilateral patellofemoral pain syndrome.

Exclusion Criteria

  • History of Recent knee surgery and Arthritis, History of Recent Dislocation and Subluxation of knee, Recent Acute Ligament and Tendon Rupture of knee, Recent Articular Capsule and Meniscus Related Injury of knee, Unresponsive to Conservative Medical Treatment.

Outcomes

Primary Outcomes

1.VISUAL ANALOGUE SCALE

Time Frame: 6 MONTHS

2.LYSHOLM KNEE SCORING SCALE

Time Frame: 6 MONTHS

3.HAND HELD DYNAMOMETER

Time Frame: 6 MONTHS

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
Lavanya M
Sponsor Class
Other [Self ]
Responsible Party
Principal Investigator
Principal Investigator

Lavanya M

College of Physiotherapy, Sri Ramakrishna Institute Of Paramedical Science

Study Sites (1)

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