Clinical observation on the treatment of cognitive dysfunction in elderly patients after total knee arthroplasty by percutaneous acupoint electrical stimulation of 'ghost point' combined with conventional points
Phase 1
Not yet recruiting
- Conditions
- POCD
- Registration Number
- ITMCTR2000003038
- Lead Sponsor
- The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
1. Patients aged 60 to 75 years old;
2. ASA I-III;
3. Patients undergoing total knee arthroplasty;
4. Patients can communicate normally.
Exclusion Criteria
1. Got encephalopathy or history of brain diseases;
2. Diagnosis of delirium grade<24 by MMSE or CAM;
3. Got nervous system disease and psychological illness include AD, stroke and mental illness;
4. Serious hearing disorder and visual impairment.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the cognitive benefits of percutaneous acupoint electrical stimulation in elderly patients post-TKA?
How does percutaneous acupoint electrical stimulation of 'ghost point' compare to standard pharmacological treatments for POCD in terms of efficacy and safety?
Are there specific biomarkers associated with response to percutaneous acupoint electrical stimulation for postoperative cognitive dysfunction in geriatric populations?
What are the potential adverse events and optimal management strategies for percutaneous acupoint electrical stimulation in elderly individuals with POCD?
What combination therapies or alternative interventions are being explored alongside percutaneous electrical stimulation for cognitive dysfunction following orthopedic surgery?