To see the effect of giving dextrose (sugar) in vein for preventing vomiting in patients after operation of gall bladder removal
Not Applicable
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitis
- Registration Number
- CTRI/2017/12/010799
- Lead Sponsor
- Safdarjung Hospital New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. American Society of Anaesthesiologists Physical Status I and II adults
2. Either gender
3. Aged 18-65 years
4. Scheduled for elective laparoscopic cholecystectomy under general anaesthesia
Exclusion Criteria
1. Patients with cardiovascular disease
2. Diabetes Mellitus
3. Jaundice, hepatic or renal disease
5. Pregnant females
6. Currently receiving opioids, steroid or antiemetic drugs
7. Increased intracranial tension
8. Cancer patients on chemotherapy or opioids
9. Abnormal blood glucose on the morning of surgery
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of post operative nausea and vomiting in patients receiving perioperative intravenous dextrose 5 percent, 10 percent or saline infusion in patients undergoing laparoscopic cholecystectomy under general anaesthesiaTimepoint: At 0, 30 min, 60 min, 90 min, 2 h, 6 h and 24 h after arrival in Post Anaesthesia Care Unit
- Secondary Outcome Measures
Name Time Method 1. To compare the severity of postoperative nausea and vomiting (PONV), the requirement of rescue antiemetics in the three groups. <br/ ><br>2. To determine the optimum dose of dextrose for prevention of PONV. <br/ ><br>3. To compare intraoperative and patient characteristics in patients with and without PONV. <br/ ><br>Timepoint: At 0, 30 min, 60 min, 90 min, 2 h, 6 h and 24 h after arrival in Post Anaesthesia Care Unit