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临床试验/NCT06631638
NCT06631638
招募中
不适用

Planned vs. Actual Acetabular Cup Position in Total Hip Arthroplasty With Non-Invasive Navigation

DePuy Orthopaedics6 个研究点 分布在 1 个国家目标入组 118 人2025年10月24日

概览

阶段
不适用
干预措施
EMPHASYS Cup with VHN
疾病 / 适应症
Osteoarthritis
发起方
DePuy Orthopaedics
入组人数
118
试验地点
6
主要终点
Composite endpoint: Acetabular Cup Position Success at 6 Weeks
状态
招募中
最后更新
19天前

概览

简要总结

The purpose of this research is to gather clinical and radiographic (X-ray) information about EMPHASYS™ acetabular shell (also called a hip 'cup') placement in total hip replacement surgery using a non-invasive surgical navigation system called VELYS™ hip navigation system with CUPTIMIZE™ Advanced Hip-Spine Analysis software.

Data collected in this study will be compared with data collected from implantations using different cup positioning instrumentation and techniques to assess performance.

注册库
clinicaltrials.gov
开始日期
2025年10月24日
结束日期
2027年12月31日
最后更新
19天前
研究类型
Interventional
研究设计
Single Group
性别
All

研究者

责任方
Sponsor

入排标准

入选标准

  • All hip replacement component devices are to be used according to the approved indications.
  • The subject is undergoing a standard of care primary uncemented hip replacement with the EMPHASYS cup and a CORAIL, EMPHASYS or ACTIS stem via the posterolateral, anterolateral, or direct lateral approach with the subject in the lateral decubitus position.
  • The subject is a candidate for implantation utilizing the VELYS Hip Navigation system with CUPTIMIZE advanced
  • Individuals who are able to speak, read, and comprehend the Informed Participant Consent Document and willing and able to provide consent for participation in the study and have authorized the transfer of his/her information to DePuy Synthes.
  • Individuals who are willing and able to complete follow-up as specified by the study protocol.
  • Individuals who are willing and able to complete the Subject Hip Outcomes questionnaires (i.e., FJS-12, EQ-5D-5L and Hip Evaluation) as specified by the study protocol.
  • Individuals who are not bedridden per the discretion of the investigator.
  • Individuals who are a minimum age of 21 years at the time of consent

排除标准

  • Active local or systemic infection.
  • Loss of musculature, neuromuscular compromise or vascular deficiency in the affected limb rendering the procedure unjustified.
  • Poor bone quality, such as osteoporosis, where, in the surgeon's opinion, there could be considerable migration of the prosthesis or a significant chance of fracture of the femoral shaft and/or the lack of adequate bone to support the implant(s).
  • Charcot's or Paget's disease.
  • The Subject is a woman who is pregnant or lactating.
  • Subject had a contralateral amputation.
  • Previous partial hip replacement in affected hip.
  • Subject has participated in a clinical investigation with an investigational product (drug or device) in the last three months.
  • Contralateral hip was replaced less than 6 months prior to surgery date.
  • Subject is currently involved in any personal injury litigation, medical-legal or worker's compensation claims.

研究组 & 干预措施

EMPHASYS Cup with VHN

EMPHASYS Cup with Non-Invasive Navigation

干预措施: EMPHASYS Cup with VHN

结局指标

主要结局

Composite endpoint: Acetabular Cup Position Success at 6 Weeks

时间窗: 6 Weeks

For an individual cup position to be considered successful, the cup's placement must satisfy all of the following criteria at 6 weeks: Inclination Success: within 10 degrees of the planned inclination via the surgeon-defined preoperative plan and version Success: within 10 degrees of the planned version via the surgeon-defined preoperative plan.

次要结局

  • Harris Hip Score(12 weeks)
  • Radiographic Outcomes(12 weeks)
  • EQ-5D-5L(12 weeks)
  • Forgotten Joint Score(6 weeks)
  • Operating Room Times(Immediately after the Surgical Procedure)
  • Leg Length Discrepancy(Immediately after the Surgical Procedure)
  • Complication Rates(90 days)
  • Harris Hip Score(12 weeks)
  • EQ-5D-5L(12 weeks)
  • Operating Room Times(Immediately after the Surgical Procedure)
  • Final Intraoperative Version(12 weeks)
  • Forgotten Joint Score(6 weeks)
  • Final Intraoperative Inclination(12 weeks)
  • Radiographic Outcomes(12 weeks)
  • Inclination Success(6 weeks)
  • Version Success(6 weeks)
  • Leg Length Discrepancy(Immediately after the Surgical Procedure)
  • Complication Rates(90 days)
  • Complication Rates(30 days)

研究点 (6)

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