NCT03466125招募中不适用
Massachusetts-wide Study of the Incidence of ATrial Fibrillation and Stroke Occurring After Discharge From Cardiac Surgery (MATRICeS)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 25,000
- 试验地点
- 1
- 主要终点
- Acute ischemic stroke
研究概览
简要总结
The purpose of the research is to identify the frequency and severity of adverse events related to atrial fibrillation that occur after discharge from hospital where the patient underwent cardiac surgery.
The Specific Aims of the proposed study are to:
- Identify the predictors of postoperative atrial fibrillation after discharge from hospital.
- Identify the frequency of readmission to hospital, or other resource use such as Emergency Department or outpatient visit, for the treatment or prophylaxis of postoperative AF and consequent stroke or bleeding outcomes.
- Identify the risks for stroke, death and other morbidity in patients after cardiac surgery and the effect of postoperative AF upon subsequent stroke or bleeding outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who underwent cardiac surgery in Massachusetts between 2012 - 2016
排除标准
- •surgical procedures that do not include coronary artery bypass graft surgery, aortic valve surgery or mitral valve surgery;
- •surgical procedures that include MAZE surgery, or pulmonary vein isolation, ventricular assist device, heart transplantation, congenital heart surgery, bacterial endocarditis, cardiac trauma, cardiac tumor, ventricular septal defect repair, left ventricular aneurysm repair, pulmonary thromboendarterectomy, sub-aortic stenosis resection or surgical ventricular restoration;
- •surgical procedures on patients that have undergone MAZE surgery, AF ablation procedures, pulmonary vein isolation or left atrial appendage resection or ablation (such as Watchman devices).
结局指标
主要结局
Acute ischemic stroke
时间窗: Up to six years after surgery
Acute ischemic stroke
Recurrent atrial fibrillation
时间窗: Up to six years after surgery
Recurrent atrial fibrillation
Mortality
时间窗: Up to six years after surgery
Mortality
次要结局
未报告次要终点
研究者
Jochen Daniel Muehlschlegel, MD
Vice Chair of Research
Brigham and Women's Hospital
研究点 (1)
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