The Prognostic Impacts and Clinical Utility of the Characteristics of New-onset Atrial Fibrillation Complicating Acute Myocardial Infarction in China
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 832
- 试验地点
- 3
- 主要终点
- All-cause death
研究概览
简要总结
To investigate the prognostic impacts of the atrial fibrillation burden (AFb) in acute myocardial infarction (AMI) patients who developed paroxysmal new-onset atrial fibrillation (NOAF) during the index AMI hospitalization.
详细描述
In the present study, investigators retrospectively reviewed the medical records of all acute MI patients who were admitted to the coronary artery unit (CCU) of Shanghai Tenth People's Hospital, KaiFeng Central Hospital, and the First Affiliated Hospital of Zhengzhou University between January 2014 and January 2022. All patients will routinely receive continuous electronic monitoring (CEM) throughout their hospital stay to detect cardiac arrhythmias including the AF events. Of these, patients with AMI without a history of AF who developed a first documented AF episode will be considered for inclusion. The AFb is measured as a percentage (%) by dividing the total AF duration by the total CEM duration.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients hospitalized for AMI including both STEMI and NSTEMI between January 2014 and January 2022 at the CCU department of Shanghai Tenth People's Hospital, KaiFeng Central Hospital, and the First Affiliated Hospital of Zhengzhou University.
- •Patients who developed a first documented AF (NOAF) during the index AMI hospitalization；
- •Adult patients (>18 years old).
排除标准
- •Patients with a medical history of pre-existing AF;
- •Patients with a medical history of rheumatic valvular disease;
- •Patients with a medical history of sick sinus syndrome;
- •Patients undergoing emergent coronary artery bypass surgery;
- •Patients' medical records with serious deficiencies and CEM data cannot be retrieved;
结局指标
主要结局
All-cause death
时间窗: From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years
Death from any cause
次要结局
- Cardiovascular death(From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years)
- Recurrent myocardial infarction(From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years)
- Ischemic stroke(From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years)
- Heart failure hospitalization(From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years)
- Major bleeding(From the time of AMI discharge until occurrence of an outcome of interest, death, or loss to follow up, maximum up to 10 years)
研究者
Ya-Wei Xu
Chief Physician
Shanghai 10th People's Hospital