CTRI/2021/03/032191进行中（未招募）4 期
A comparative study of preoperative magnesium sulphate nebulisation and budesonide nebulisation in reducing the incidence and severity of post operative sore throat
Laishram Rani Devi1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2021年3月24日最近更新:
试验速览
- 阶段
- 4 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To compare the effectiveness of magnesium sulphate and budesonide in reducing the incidence and severity of post operative Sore throat
研究概览
简要总结
A double blinded, randomised control trial will be conducted in my Institution to compare the effectiveness of preoperative nebulisation of two drugs Magnesium sulphate and Budesonide in reducing the incidence and severity of Postoperative Sore Throat in patients undergoing elective surgery under general anaesthesia with endotracheal intubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who have signed written informed consent.
- •Patients with ASA grade I-II Patients undergoing Elective surgery under general anaesthesia with endotracheal intubation.
- •Patients undergoing surgery in supine position.
排除标准
- •Patient refusal.
- •History of known allergy to the drugs.
- •History of cough or Upper Respiratory Tract illness.
- •History of Respiratory diseases like COPD, Asthma etc.
- •History of smoking Mallampati score >II More than one attempt of intubation.
- •Patients undergoing oral or nasal surgeries.
- •Patients on long term anti-inflammatory analgesic medications.
结局指标
主要结局
To compare the effectiveness of magnesium sulphate and budesonide in reducing the incidence and severity of post operative Sore throat
时间窗: 0hr, 2hrs, 24hrs and 48hrs after extubation
次要结局
- To assess the hemodynamic profile of the nebulised drugs and their acceptability score(Before and After nebulisation, Intraoperatively)
研究者
研究点 (1)
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