IRCT20200312046749N1招募中2 期
Evaluation the efficacy of Tumor Necrosis Factor alpha inhibitor in COVID-19 outcomes: a prospective clinical trial study.
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Confirmed the COVID-19 disease with one or more of these: fever, dry cough, dyspnea and one or more of below: positive SARS-COV2 PCR •Characteristic changes of SARS-COV2 in chest CT scan such as bilateral ground grass opacity in bases of the lungs ( confirmation with the radiologist)
- •Age>18 years old
- •Signing inform consent from the patient or patient? s accompaniment
- •No manifestations of bacterial infection
- •No history of rheumatologic disorders
- •No history of cancer for the last 1 year.No history of immunodeficiency (primary or acquired)
- •No manifestations, history and radiologic parameters according to active or latent TB
- •No diabetes or autoimmune hepatitis
- •No history of immunosuppressive treatment in the last 6 months
- •No history of growth hormone, Testosterone and any Anabolic steroids in the last one month
- •No history of Corticosteroid therapy (>30 mg/m2) for > 5 days in the last one month
- •No history of Corticosteroid pulses or IVIG treatments for last one month
- •No history of Biologics treatment for the last 6 months
排除标准
- •Administration of corticosteroids pulses and/or IVIG in the disease process or one month after anti-TNF prescription.
- •Unwillingness of involved patients to continue this research.
研究者
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