Outpatient Lung Impedance-Guided Preventive Therapy in Patients With Chronic Heart Failure (CHF)
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Chronic Congestive Heart Failure
- Sponsor
- Hillel Yaffe Medical Center
- Enrollment
- 300
- Locations
- 1
- Primary Endpoint
- Reduction of hospitalization for acute heart failure
- Last Updated
- 9 years ago
Overview
Brief Summary
Patients suffering from Chronic Heart Failure (CHF) are hospitalized for acute heart failure (AHF) several times a year. Currently, we have no method for prediction of future developments of AHF. In our center we have investigated the monitoring of lung impedence as a predictor for future deterioration. It was found that a decrease in lung impedence of more than 15% from normal value predicts AHF development with sensitivity of 98%. In this study we try to prove the hypothesis that preventive treatment according to lung impedence value may prevent future hospitalizations for AHF and improve clinical outcome.
Patients recruited by year:
2011 - 50; 2012 - 25; 2013 - 35; 2014 - 30; 2015 - 50; 2016 - 5
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients suffering from CHF, NYHA II-IV class
- •LV lower than 35% to LV lower than 45%
Exclusion Criteria
- •Patients with additional disease with life-expectancy of less than 2 years
Outcomes
Primary Outcomes
Reduction of hospitalization for acute heart failure
Time Frame: Five years
Secondary Outcomes
- Improved clinical outcome for CHF patients(Five years)