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Clinical Trials/NCT02490189
NCT02490189
Completed
Not Applicable

Comparative Trial of a Mindfulness-based Intervention Versus Cognitive Behavior Therapy for Social Anxiety Disorder

Hopital Montfort2 sites in 1 country97 target enrollmentJuly 25, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Social Anxiety Disorder
Sponsor
Hopital Montfort
Enrollment
97
Locations
2
Primary Endpoint
Liebowitz Social Anxiety Scale
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

To conduct a prospective, randomized trial to compare the efficacy of a group mindfulness-based intervention adapted for social anxiety disorder (MBI-SAD) versus cognitive behavior group therapy (CBGT).

Detailed Description

The main aim of this comparative trial is to determine if the MBI-SAD will be noninferior to CBGT in improving core symptoms of social anxiety disorder, depressive symptoms, self, esteem, disability and quality of life. A secondary aim is to examine whether treatment gains are maintained over a 6-month period. Exploratory aims of the study are to: 1) determine if the MBI-SAD enhances self-compassion and mindfulness relative to CBGT; 2) determine if changes in self-compassion and mindfulness mediate the clinical response to the MBI-SAD; and 3) explore moderators of treatment response.

Registry
clinicaltrials.gov
Start Date
July 25, 2015
End Date
February 21, 2018
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Diana Koszycki

Professor and Research Chair in Mental Health

Hopital Montfort

Eligibility Criteria

Inclusion Criteria

  • DSM-5 diagnosis of social anxiety disorder (SAD) of at least moderate severity
  • Montgomery Asberg Depression Rating Scale score ≤ 25
  • Comorbid depressive disorders, panic disorder, agoraphobia, generalized anxiety disorder, specific phobias, eating disorders are allowed as long as the SAD is primary and predominates the clinical picture.

Exclusion Criteria

  • Coexisting Axis I disorders excluding those listed in the inclusion criteria
  • Coexisting medical conditions that can alter the clinical presentation of SAD (e.g. Parkinson's disease)
  • Lifetime history of bipolar disorder or psychotic symptoms
  • Substance-related disorders in the last 12 months
  • Acutely suicidal or history of suicide attempt in the past five years
  • History of non-suicidal self-injurious behavior in the last 12 months
  • Currently receiving psychotherapy
  • Currently engaged in a regular meditation or yoga practice
  • Unable to attend weekly group sessions

Outcomes

Primary Outcomes

Liebowitz Social Anxiety Scale

Time Frame: Change from baseline to week 12 and 6-month follow-up

A 24-item clinician-rated scale that assesses fear and avoidance of social performance and social situations.

Secondary Outcomes

  • Beck Depression Inventory(Change from baseline to week 12 and 6-month-follow-up)
  • Social Adjustment Scale-Self Report Revised(Change from baseline to week 12 and 6-month follow-up)
  • Satisfaction with Life Questionnaire(Change from baseline to week 12 and 6-month follow-up)
  • Clinical Global Impression Improvement Ratings(Change from baseline to week 12 and 6-month follow-up)
  • Rosenberg Self-Esteem Scale(Change from baseline to week 12 and 6-month follow-up)
  • Social Phobia Inventory(Change from baseline to week 12 and 6-month follow-up)

Study Sites (2)

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