A comparative study on steroid therapy in children with nephrotic syndrome

Not Applicable

Recruiting

• Conditions: ephrotic syndrome

• Registration Number: SLCTR/2016/027
• Lead Sponsor: niversity Renal Clinic

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-08-20

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 64

Inclusion Criteria

1. Patients presenting with nephrotic syndrome between 1 yr to 12 yrs of age.

2. 1st episode of nephrotic syndrome, defined as patients with gross proteinuria (+++ or more) with UPcr > 200mg/mmol hypoalbuminemia (albumin>2.5g/dl) and odema.

3. Relapse of nephrotic syndrome, defined as gross proteinuria of +++ or more or UPcr >200mg/mmol for more than 3 days in a child who has been previously diagnosed of having nephrotic syndrome.

Exclusion Criteria

1. Patients who are resistance to prednisolone, defined as Faliure to achieve remission after 28 days of daily prednisolone given at a dose of 60mg/m2/day
2. Remission achieved after more than 28 days of daily prednisolone.
3. Nephroic syndrome secondary to systemic diseases
4. Patients having gross hematuria

Study & Design

• Study Type: Interventional
• Study Design: Not specified