The effects of exercise training on small blood vessel health in individuals with type 2 diabetes and in overweight and obese older participants.
Not Applicable
- Conditions
- Diet and Nutrition - Obesitytype 2 diabetesobesityMetabolic and Endocrine - Diabetes
- Registration Number
- ACTRN12623000724673
- Lead Sponsor
- The University of Western Australia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Age range between 45 and 70 years old;
BMI greater than 30 kg/m² or BMI 27-30 kg/m² with at least one established weight-related cardiometabolic co-morbidity, or type 2 diabetes diagnosis >1 year.
Exclusion Criteria
Type 2 diabetes diagnosis <1 year
Insulin and/or sulphonylurea medication
Glycated haemoglobin >8.5
Advanced microvessel complications including ulceration, decrease kidney function and/or eye complications which require treatment
Macrovascular complications including a history of unregulated high blood pressure, myocardial infarction and/or cerebrovascular disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Indices of microvascular function derived from optical coherence tomography (OCT): microvascular density, diameter, blood speed and blood flow. They are a composite primary outcomes and will not be assessed independently.[12 weeks post-commencement of intervention]
- Secondary Outcome Measures
Name Time Method