Effect of a Probiotic-based Product on Blood Pressure
Not Applicable
Completed
- Conditions
- Blood Pressure
- Registration Number
- NCT01989702
- Lead Sponsor
- Probi AB
- Brief Summary
The aim of the present study was to examine the efficacy of a probiotic-based product on either reducing hypertension or preventing a high normal blood pressure from reaching hypertensive levels.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 142
Inclusion Criteria
- Healthy individuals at the age of 40-75 years.
- Blood-pressure >140/90 mmHg that has been confirmed at 2-3 separate occasions or represents the mean value of a 24-hour measurement.
- Triglycerides >1,7 mmol/L and/or HDL <1 mmol/L (men)/1,29 mmol/L (women).
- Fasting plasma glucose levels >5,6 mmol/L and/or waist circumference >102 cm (men)/88 cm (women).
- BMI <40.
Exclusion Criteria
- Medically treated allergy or allergy to any of the ingredients of the study product.
- Medication for high levels of blood lipids.
- Metabolic disease, such as type one diabetes.
- Confirmed diseases of the heart, liver of kidneys.
- Chronic inflammatory disease requiring medication.
- Pregnant or nursing.
- Regular intake of other probiotic products (5-7 days per week during the last three months before inclusion into the study).
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Changes from baseline in systolic and diastolic blood pressure after 3 months of probiotic intervention Baseline, 3 months
- Secondary Outcome Measures
Name Time Method Changes from baseline of blood parameters, such as inflammatory markers and blood lipids, linked to increased risk for cardiovascular diseases Baseline, 3 months