Study of Arithmetic Abilities of Children With 22q11.2 Deletion Syndrome Aged From 4 to 11 Years Old
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 41
- 试验地点
- 2
- 主要终点
- Percentage of impaired scaled score
研究概览
简要总结
The study ARITH22 will investigate the role of visuo-spatial attention on arithmetic abilities of children with 22q11.2 deletion syndrome.
详细描述
Children with 22q11.2 deletion syndrome often have arithmetic learning disability because of magnitude representation impairment. Previous works suggested that magnitude representation impairment could be a result of endogenous visuo-spatial attention dysfunction in 22q11.2DS. Nevertheless this relationship is still poor explored. The influence of visuo-spatial abilities on arithmetic achievement could also be modulated by developmental age. The study ARITH22 will test these hypotheses thanks to magnitude comparisons tasks, in children with 22q11.2 deletion syndrome and matched children without developmental disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 4 Years 至 11 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosis of 22q11.2 deletion syndrome or no developmental disease
- •Aged from 4 to 11 years old
- •French language
排除标准
- •Diagnosis of intellectual deficiency according to DSM 5 criteria
- •Drug prescribed for somatic condition that could influence cerebral functioning
结局指标
主要结局
Percentage of impaired scaled score
时间窗: single day
percentage of impaired scaled score at ZAREKI-R
次要结局
- Percentage of correct responses(single day)
- Mean reaction time(single day)