ISRCTN11992428
Active, not recruiting
Phase 3
A Randomised controlled trial to Evaluate the effectiveness and cost benefit of prescribing high dose FLuoride toothpaste in preventing and treating dEntal Caries in high-risk older adulTs
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Dental Caries
- Sponsor
- Manchester University NHS Foundation Trust
- Enrollment
- 1161
- Status
- Active, not recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
2019 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/31126270 protocol (added 29/05/2019)
Investigators
Eligibility Criteria
Inclusion Criteria
- •Current inclusion criteria as of 15/07/2022:
- •1\. Patients attending dental practices participating in the trial
- •2\. Aged 50 years or older
- •3\. Diagnosis of active coronal caries (into dentine) in the last 12 months which may/may not have been treated, or any root caries; and\\or other risk factors as determined by their GDP
- •4\. Living in any residential setting
- •5\. Receive their dental care in part or fully as an NHS patient
- •6\. Patients whose GDP decides prescription of high concentration fluoride toothpaste is appropriate
- •Previous inclusion criteria:
- •1\. Patients attending dental practices participating in the trial
- •2\. Aged 50 years of age or older
Exclusion Criteria
- •Current exclusion criteria as of 15/07/2022:
- •1\. Currently prescribed (by GDP or GP) high concentration fluoride toothpaste (for GDPs, prescription must have been issued at last examination visit)
- •2\. Unable to provide informed consent
- •3\. Hypersensitivity for sodium fluoride and/or other ingredients used in 5000ppm toothpaste
- •4\. Are living in the same household as someone already recruited to REFLECT, or someone who is routinely using a high concentration fluoride toothpaste
- •Previous exclusion criteria:
- •1\. Currently prescribed high concentration fluoride toothpaste
- •2\. Unable to provide informed consent
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
A study to examine health effect indicators when a smoker switches to using a tobacco heating productISRCTN81075760British American Tobacco (Investments) Ltd506
Completed
Not Applicable
EEPIC: Enhancing employability through positive interventions for increasing career potential. A high support career guidance intervention to improve the well-being and employability of the long term unemployed in IrelandISRCTN16801028Maynooth University120
Completed
Phase 4
A Study of Concerta XL on reducing ADHD symptoms and behavioural problems in adult offenders with ADHDISRCTN16827947King's College London200
Completed
Not Applicable
The effectiveness of bridging from emergency to regular contraceptioReproductive healthPregnancy and ChildbirthISRCTN70616901niversity of Edinburgh636
Completed
Not Applicable
MAGENTA: Managed activity graded exercise in teenagers and pre-adolescentsTopic: ChildrenSubtopic: All DiagnosesDisease: All DiseasesNervous System DiseasesPaediatric chronic fatigue syndrome, myalgic encephalomyelitis (CFS/ME)ISRCTN23962803Royal National Hospital for Rheumatic Disease (UK)237