CTRI/2017/07/009132Completed未知
Effect of yoga therapy on disease activity, cardiac autonomic functions and inflammatory markers in patients of Rheumatoid arthritis - A randomized control trial
Jawaharlal Institute of Postgraduate Medical Education and Research0 sites183 target enrollmentStarted: TBDLast updated:
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Enrollment
- 183
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •1.Both genders between 18 and 60 years of age.
- •2.Newly onset Rheumatoid arthritis patients having disease duration less than 1 year with diagnosis of RA according to the 2010 ACR/EULAR criteria.
- •3.Rheumatoid arthritis patients partially responding to methotrexate therapy.
- •All patients with rheumatoid arthritis (RA) attending the OP or IP services of the Department of Immunology after thorough clinical and laboratory investigations, they will receive methotrexate (unless contraindicated) as initial DMARD (Disease-Modifying Antirheumatic Drugs ) therapy 10 mg per week, escalated @ 5 mg / week, every 2 weeks up to a maximum of 25 mg per week or maximum tolerated dose whichever is less at the end of 6 weeks. Patients will receive NSAlDs (Diclofenac 50 mg twice a day and SOS basis for control of pain). Treatment response will be assessed using EULAR response criteria at the end of three months or after 6 continuous weeks of stable combination DMARD therapy whichever is later. Based on the treatment response patients will be classified as â??good, moderate and poor responderâ??. Patients with complete response to methotrexate will continue the same medication. Whereas, those with poor response will be offered additional DMARD therapy (triple therapy). These two groups will not be recruited in the study. The patients labeled as â??partial respondersâ?? will be continued on methotrexate for a further period of 3 months. They will be enrolled in the study during this phase of stable methotrexate therapy.
Exclusion Criteria
- •1.Diabetes mellitus
- •2.Uncontrolled Hypertension (JNC 7 report)
- •3.Rheumatoid arthritis patients with apparent deformities.
- •4.Any other neuromuscular disorder.
- •5.Any other Auto immune disorders.
- •6.Patients who have undergone yoga therapy or any other bio-feedback techniques in last one year.
- •7.History of alcoholism or drug abuse within 1 year of screening.
- •8.Intra-articular steroid injections with in 4 weeks of screening.
Investigators
Similar Trials
Not yet recruiting
Not Applicable
Effects study of yoga therapy on the association of mental illness with metabolic disorders, including the carbonyl stressSchizophreniaJPRN-UMIN000013746Tokyo Metropolitan Matsuzawa Hospital60
Completed
Not Applicable
Effect of Yoga and Nature cure therapy on weight,heart status and mind of thyroid patientsCTRI/2020/07/026734Dr Sharada Shetty P S60
Completed
Not Applicable
Effect of yoga and naturopathy therapies on nerves in sugar patienstsCTRI/2020/07/026842DR SOMISETTY KOUSHIK GUPTA76
Recruiting
Phase 1
Effect of Yoga in patients with Vasovagal SyncopeCTRI/2017/12/010917Ministry of AYUSH
Completed
Not Applicable
Yoga for migraine headache managementCTRI/2021/11/038100Kaivalyadham SMYM Samiti41