Detecting if Change in the exhaled Carbon Dioxide signifies change in Cardiac output for the prediction of response to fluids in adult patients undergoing cancer surgery
Not Applicable
- Conditions
- Health Condition 1: C189- Malignant neoplasm of colon, unspecifiedHealth Condition 2: C229- Malignant neoplasm of liver, not specified as primary or secondaryHealth Condition 3: C259- Malignant neoplasm of pancreas, unspecifiedHealth Condition 4: C20- Malignant neoplasm of rectumHealth Condition 5: C169- Malignant neoplasm of stomach, unspecifiedHealth Condition 6: C569- Malignant neoplasm of unspecifiedovaryHealth Condition 7: C55- Malignant neoplasm of uterus, partunspecified
- Registration Number
- CTRI/2022/04/041695
- Lead Sponsor
- Sohan Lal Solanki
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Adult (Age 18 and above)
2. Giving informed consent
3. ASA PS 1, 2, 3
4. Planned for surgeries routinely requiring radial artery cannulation and the FlotracTM and Vigileo EV1000 / Volumeview cardiac output monitor for perioperative care used as a part of routine intraoperative management
Exclusion Criteria
1. Planned for open thoracic surgery
2. History of Cardiac arrhythmias/ intraoperative Cardiac arrhythmias
3. Heart failure: both systolic and diastolic heart failure (with or without reduced Left ventricular ejection fraction)
4. Severe restrictive/obstructive lung disease (MRC score 3 and above)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to determine whether the delta ETCO2 after a fluid challenge test identifies fluid responsiveness, i.e., increase in stroke volume index (dSVI) and Cardiac Index (dCI) 10%.Timepoint: After 1 minute of fluid boluses over 10 minutes.
- Secondary Outcome Measures
Name Time Method To compare the ability to delta ETCO2 to discriminate between fluid responders and non-responders with that of PPV and Stroke Volume Variation (SVV)Timepoint: After 1 minute of fluid boluses over 10 minutes.