The Effect of Dry Needling and Prolotherapy on Pain, Function, and Quality of Life in Patients With Cervical Radiculopathy.

Not Applicable

Active, not recruiting

• Conditions: Cervical Radiculopathy
• Interventions: Diagnostic Test: conventional treatment with Prolotherapy; Other: Dry Needling and conventional treatment

• Registration Number: NCT06457529
• Lead Sponsor: Superior University

Brief Summary

Cervical radiculopathy is characterized by neurological dysfunction caused by compression and inflammation of the spinal nerves or nerve roots of the cervical spine. Rolotherapy is a regenerative therapeutic method that consists of injecting irritant solutions into the injured areas.

Detailed Description

Hyperosmolar dextrose is the most common agent. Administering proliferant substances can accelerate the tissue healing process by inducing cellular rupture and inflammatory response, leading to collagen deposition, cellular growth factor production, and regeneration. Dry needling used to relieve trigger point release in deep and superficial muscles. Both treatment interventions will apply to cervical radiculopathy patients to measure the effectiveness of treatment.

Study Timeline

• Study Start: 2023-10-01
• Primary Completion: 2024-05-01
• Status Verified: 2024-06
• Study First Submitted: 2024-06-10
• Study First Submitted QC: 2024-06-10
• Last Update Submitted: 2024-06-10
• Study First Posted: 2024-06-13
• Last Update Posted: 2024-06-13
• Study Completion: 2024-09-30

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Age group between 20-50 years
• Both male and female
• Unilateral pain starting in the cervical spine and radiating to the upper limb.
• Pain aggravated by upper limb movement
• Restricted range of motion of arm

Exclusion Criteria

• History of Spinal infection
• Spinal Cord Injury
• History of Vertebral tumor and factures
• History of cervical or intracranial surgery
• History of Radiating pain to bilateral upper limb.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
conventional treatment with Prolotherapy	conventional treatment with Prolotherapy	-
Dry Needling and conventional treatment	Dry Needling and conventional treatment	-

Primary Outcome Measures

Name	Time	Method
Neck Disability Index	12 Months	The NDI has become a standard instrument for measuring self-rated disability due to neck pain and is used by both clinicians and researchers. Each of the 10 items scores from 0 to 5. The maximum score is 50. The obtained score can be multiplied by two to produce a percentage score
WHO Quality of Life	12 months	The QOLS is a reliable and valid instrument for measuring quality of life from the perspective of the patient. It focuses on domains that come from the qualitative descriptions of a wide range of adults across gender, cultural and language groups.Each individual item of the WHOQOL-BREF is scored from 1 to 5 on a response scale, which is stipulated as a five-point ordinal scale. The scores are then transformed linearly to a 0-100-scale (16, 17). The physical health domain includes items on mobility, daily activities, functional capacity, energy, pain, and sleep

Trial Locations

Locations (1)

Iqbal Mahmooda Hospital, Iffat Anwar Medical Complex and Life line Hospital; 🇵🇰 Lahore, Punjab, Pakistan