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Clinical Trials/NCT07536542
NCT07536542
Not yet recruiting
Not Applicable

Effects of Dual-Task Training on Upper Extremity Function and Muscle Thickness in Parkinson's Disease

Ankara University1 site in 1 country38 target enrollmentStarted: April 24, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
38
Locations
1
Primary Endpoint
Upper Extremity Function

Overview

Brief Summary

The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease. The main questions it aims to answer are:

Does dual-task training improve upper extremity function in individuals with Parkinson's disease? Does dual-task training lead to changes in upper extremity muscle thickness measured by ultrasonography?

Researchers will compare a dual-task training group with a control group receiving routine care to determine whether 8 weeks of dual-task training results in greater improvements in upper extremity outco

Participants will:

complete baseline and post-intervention assessments of upper extremity function, muscle thickness, grip strength, and pinch strength be assigned to either a control group or a dual-task training group receive dual-task training 3 days per week for 8 weeks if assigned to the intervention group

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
40 Years to 65 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Diagnosis of idiopathic Parkinson's disease confirmed by a neurologist
  • Modified Hoehn and Yahr stage 2 to 3
  • No medication or dosage change within the last 6 months
  • Cognitive capacity sufficient to understand and follow instructions, defined as Montreal Cognitive Assessment score ≥21
  • Voluntary participation with written informed consent

Exclusion Criteria

  • Atypical or secondary parkinsonism
  • Advanced orthopedic condition affecting the upper extremity
  • Surgery, trauma, or immobilization involving the upper extremity within the last 6 months
  • Wound or dermatological condition preventing upper extremity ultrasonographic evaluation
  • Severe visual or hearing loss
  • Severe depression, psychosis, or communication difficulty
  • Any additional health problem preventing regular participation in the study

Arms & Interventions

Dual-Task Training Group

Experimental

Participants will receive dual-task training in addition to their routine daily activities. The training program will be performed 3 times per week for 8 weeks, with each session lasting 60 minutes and consisting of combined motor and cognitive tasks.

Intervention: Dual-Task Training (Behavioral)

Control Group

No Intervention

Participants will continue their routine daily activities without receiving any additional exercise, training, or rehabilitation intervention during the study period.

Outcomes

Primary Outcomes

Upper Extremity Function

Time Frame: Baseline and 8 weeks

Upper extremity function will be assessed using the Purdue Pegboard Test. Performance will be recorded as the number of pins placed within the specified time for dominant hand, nondominant hand, and both hands; higher scores indicate better fine motor performance and manual dexterity.

Upper Extremity Muscle Thickness

Time Frame: Baseline and 8 weeks

Muscle thickness of the deltoid, biceps brachii, triceps brachii, and forearm flexor muscles will be measured using ultrasonography. The mean of three repeated measurements for each site will be recorded in millimeters.

Hand Grip Strength

Time Frame: Baseline and 8 weeks

Hand grip strength will be measured using a Jamar hydraulic hand dynamometer according to the ASHT protocol. The mean of three trials will be recorded.

Pinch Strength

Time Frame: Baseline and 8 weeks

Lateral pinch, three-jaw chuck pinch, and two-point pinch strength will be assessed using a pinch meter. The mean of three trials will be recorded in kilograms or Newtons.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Büşra Seçkinoğulları Korkusuz

Assist. Prof. Dr

Ankara University

Study Sites (1)

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