Effects of Dual-Task Training on Upper Extremity Function and Muscle Thickness in Parkinson's Disease
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Upper Extremity Function
研究概览
简要总结
The goal of this clinical trial is to investigate the effects of dual-task training on upper extremity function and muscle thickness in individuals with Parkinson's disease. The main questions it aims to answer are:
Does dual-task training improve upper extremity function in individuals with Parkinson's disease? Does dual-task training lead to changes in upper extremity muscle thickness measured by ultrasonography?
Researchers will compare a dual-task training group with a control group receiving routine care to determine whether 8 weeks of dual-task training results in greater improvements in upper extremity outco
Participants will:
complete baseline and post-intervention assessments of upper extremity function, muscle thickness, grip strength, and pinch strength be assigned to either a control group or a dual-task training group receive dual-task training 3 days per week for 8 weeks if assigned to the intervention group
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of idiopathic Parkinson's disease confirmed by a neurologist
- •Modified Hoehn and Yahr stage 2 to 3
- •No medication or dosage change within the last 6 months
- •Cognitive capacity sufficient to understand and follow instructions, defined as Montreal Cognitive Assessment score ≥21
- •Voluntary participation with written informed consent
排除标准
- •Atypical or secondary parkinsonism
- •Advanced orthopedic condition affecting the upper extremity
- •Surgery, trauma, or immobilization involving the upper extremity within the last 6 months
- •Wound or dermatological condition preventing upper extremity ultrasonographic evaluation
- •Severe visual or hearing loss
- •Severe depression, psychosis, or communication difficulty
- •Any additional health problem preventing regular participation in the study
研究组 & 干预措施
Control Group
Participants will continue their routine daily activities without receiving any additional exercise, training, or rehabilitation intervention during the study period.
Dual-Task Training Group
Participants will receive dual-task training in addition to their routine daily activities. The training program will be performed 3 times per week for 8 weeks, with each session lasting 60 minutes and consisting of combined motor and cognitive tasks.
干预措施: Dual-Task Training (Behavioral)
结局指标
主要结局
Upper Extremity Function
时间窗: Baseline and 8 weeks
Upper extremity function will be assessed using the Purdue Pegboard Test. Performance will be recorded as the number of pins placed within the specified time for dominant hand, nondominant hand, and both hands; higher scores indicate better fine motor performance and manual dexterity.
Upper Extremity Muscle Thickness
时间窗: Baseline and 8 weeks
Muscle thickness of the deltoid, biceps brachii, triceps brachii, and forearm flexor muscles will be measured using ultrasonography. The mean of three repeated measurements for each site will be recorded in millimeters.
Hand Grip Strength
时间窗: Baseline and 8 weeks
Hand grip strength will be measured using a Jamar hydraulic hand dynamometer according to the ASHT protocol. The mean of three trials will be recorded.
Pinch Strength
时间窗: Baseline and 8 weeks
Lateral pinch, three-jaw chuck pinch, and two-point pinch strength will be assessed using a pinch meter. The mean of three trials will be recorded in kilograms or Newtons.
次要结局
未报告次要终点
研究者
Büşra Seçkinoğulları Korkusuz
Assist. Prof. Dr
Ankara University