Evaluating the Use of Acute Intermittent Hypoxia to Improve Symptoms in Persons With Multiple Sclerosis

Shirley Ryan AbilityLab1 site in 1 country10 target enrollmentJune 18, 2018

ConditionsMultiple Sclerosis, Relapsing-Remitting

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Multiple Sclerosis, Relapsing-Remitting
Sponsor: Shirley Ryan AbilityLab
Enrollment: 10
Locations: 1
Primary Endpoint: Voluntary Ankle Strength
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The overall objective of this project is to investigate the effectiveness of Acute Intermittent Hypoxia (AIH), to improve muscle strength and activity level in individuals with relapsing-remitting MS.

Registry

clinicaltrials.gov

Start Date

June 18, 2018

End Date

December 30, 2019

Last Updated

6 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Shirley Ryan AbilityLab

Responsible Party

Principal Investigator

Milap Sandhu

Principal Investigator

Shirley Ryan AbilityLab

Eligibility Criteria

Inclusion Criteria

•Have relapsing-remitting MS
•Volitional ankle plantar flexion strength in at least one leg
•Are relapse free for 30 days
•Patient-Determined Disease Steps scale score between 3 and 5 (3=gait disability to 5=late cane, need cane to walk 25 feet)

Exclusion Criteria

•Currently taking antispasticity medications,
•Have cardiovascular or respiratory/pulmonary disorders, metabolic dysfunction, or prior diagnoses of obstructive sleep apnea
•Pregnant or nursing women (safety for developing fetus or infant is unknown)
•Cognitive concerns (must be able to consent to study, follow steps)