Clinical Comparative Analysis of Bretschneider and St. Thomas Cardioplegia Solution in Case of Mitral Valve Repair Via Anterolateral Right Thoracotomy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Creatin-Phosphokinase (CK) (U/l)
研究概览
简要总结
Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy is done in cardioplegia with a cardioplegic solution, either HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St. Thomas (a crystalloid extracellular solution).
This study investigates HTK-Bretschneider versus St. Thomas cardioplegic solution regarding peri- and postoperative outcome, especially for cardiac biomarkers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy done in cardioplegia with a cardioplegic solution, either HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St. Thomas (a crystalloid extracellular solution).
排除标准
- •Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy done in cardioplegia with cardioplegic Solutions other than HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St. Thomas (a crystalloid extracellular solution).
结局指标
主要结局
Creatin-Phosphokinase (CK) (U/l)
时间窗: perioperative during minimal invasive surgery
cardial biomarker for myocardial damage
high specific troponin T (hs-TrT) (μg/l)
时间窗: perioperative during minimal invasive surgery
cardial biomarker for myocardial damage
Creatinkinase Muscle- Brain (CK-MB) (U/l)
时间窗: perioperative during minimal invasive surgery
cardial biomarker for myocardial damage
次要结局
- mortality rate(from minimal invasive surgery until 30 days post surgery)
- length of stay in intensive care unit (days)(from minimal invasive surgery until 30 days post surgery)