Effect of drug therapy in the treatment of migraine

Phase 3

Not yet recruiting

• Conditions: Migraine without aura, myofascial pain syndromes, Limitations of the Cervical Range of Motion; C10.228.140.546.399.750.450; C05.651.550

• Registration Number: RBR-6kvx74
• Lead Sponsor: Faculdade de Medicina de Ribeirão preto da Universidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-04-26
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: not yet recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Will be included 50 individuals with migraine, female, aged between 18 and 55. Will be considered only patients with at least two attacks and a maximum of 12 days of pain per month, with disease duration longer than one year, they are only in ambulatory treatment with amitriptyline up to 25 mg for at least 3 months.

Exclusion Criteria

Will be excluded women with diagnoses of other concurrent headache diagnosis of migraine, history of cervical trauma and face, with uncontrolled systemic diseases affecting the musculoskeletal system, peripheral nervous system diseases, which have physical therapy in the last one year specific to region or craniocervical posture and have some clinical contraindication to the use of amitriptyline as cardiac arrhythmias, glaucoma and epilepsy.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduced Frequency (in days) and intensity (in hours) of by Migraine headache diary.

Secondary Outcome Measures

Name	Time	Method
Increased pressure pain threshold in kg in muscle in craniofacial demonstrated displey pressure algometer.<br>;Increase in neck range of motion in degrees using the Cervical Range of Motion (CROM).<br>