Comparison the therapeutic effects of liposomal tranexamic acid form and conventional form of Hydroquinone on melasma patients
Phase 2
- Conditions
- Melasma.Melasma
- Registration Number
- IRCT201403173862N10
- Lead Sponsor
- Research Council of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
clinically diagnosed melisma patients, age more than 18 years old.
Exclusion criteria: pregnancy and breast feeding, simultaneous hormonal disease, drug use including anti barbiturate drugs, recent hormonal and corticosteroids treatments, patients who treated by bleaching therapy on the last four months, patients underwent laser during the last six month, patients who don’t refer on follow up periods, any side effects which canceled the treatment.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of pigmentation. Timepoint: Monthly untill the end of 12 weeks. Method of measurement: Melasma Area and Severity Index.
- Secondary Outcome Measures
Name Time Method Melasma severity. Timepoint: Comparison melasma severity in baseline and terminal of 3 months treatment course. Method of measurement: Melasma Area and Severity Index.