Long-term Outcomes of Critical Illness Survivors：a Prospective Cohort Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Intensive Care Units
- Sponsor
- Jian-jun Yang
- Enrollment
- 200
- Locations
- 2
- Primary Endpoint
- Survival rate of ICU survivors
- Last Updated
- 6 years ago
Overview
Brief Summary
The goal of this study is to assess the Long-term Outcomes of Critical Illness Survivors,including physical, psychological, and cognitive sequelae.
Detailed Description
An increasing number of patients survive critical illness; however, the evidence reveals that over the same period the number of patients being sent to rehabilitation settings have tripled . For those who do survive, the latest data indicate that 50-70% of ICU "survivors" will suffer cognitive impairment and 60-80% of "survivors" will suffer functional impairment or ICU-acquired weakness (ICU-AW).Still,there is a lack valid data on the long-term impact on morbidity from prospective observational studies. Therefore, the investigators designed an observational cohort which cover a broader range of outcomes to quantify long-term physical, psychological, and cognitive impairment after intensive care unit (ICU).Intensive Care Unit patients survive from critical illness will be approached for study recruitment and participation.Survival rate,Quality of life,Cognitive impairments,Depression and anxiety,PTSD,Physical activity,Neuromuscular impairment will be assessed 3 or 6 months after ICU discharge.
Investigators
Jian-jun Yang
Director,Department of Anesthesiology
Zhongda Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients aged \>17 years
- •Patients in intensive care unit(ICU) with at least one organ or system dysfunction,such as respiratory failure, cardiogenic shock,or septic shock.
Exclusion Criteria
- •Refuse to participate
- •Death before ICU discharge
- •pre-existing cognitive impairment, malignant tumor
Outcomes
Primary Outcomes
Survival rate of ICU survivors
Time Frame: 3 or 6 months after ICU discharge
Critically ill patients discharged from ICU are defined as survivors
Secondary Outcomes
- Assessment in depression and anxiety(3 or 6 months after ICU discharge)
- Assessment in PTSD(3 or 6 months after ICU discharge)
- Assessment in Physical dysfunction(3 or 6 months after ICU discharge)
- Assessment of life quality(3 or 6 months after ICU discharge)
- Assessment in Cognitive impairments(3 or 6 months after ICU discharge)
- Neuromuscular impairment(3 or 6 months after ICU discharge)
- Patients' care and support needs;social and economical consequences(3 or 6 months after ICU discharge)