Long-term Outcomes of Critical Illness Survivors：a Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- Survival rate of ICU survivors
研究概览
简要总结
The goal of this study is to assess the Long-term Outcomes of Critical Illness Survivors,including physical, psychological, and cognitive sequelae.
详细描述
An increasing number of patients survive critical illness; however, the evidence reveals that over the same period the number of patients being sent to rehabilitation settings have tripled . For those who do survive, the latest data indicate that 50-70% of ICU "survivors" will suffer cognitive impairment and 60-80% of "survivors" will suffer functional impairment or ICU-acquired weakness (ICU-AW).Still,there is a lack valid data on the long-term impact on morbidity from prospective observational studies. Therefore, the investigators designed an observational cohort which cover a broader range of outcomes to quantify long-term physical, psychological, and cognitive impairment after intensive care unit (ICU).Intensive Care Unit patients survive from critical illness will be approached for study recruitment and participation.Survival rate,Quality of life,Cognitive impairments,Depression and anxiety,PTSD,Physical activity,Neuromuscular impairment will be assessed 3 or 6 months after ICU discharge.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged >17 years
- •Patients in intensive care unit(ICU) with at least one organ or system dysfunction,such as respiratory failure, cardiogenic shock,or septic shock.
排除标准
- •Refuse to participate
- •Death before ICU discharge
- •pre-existing cognitive impairment, malignant tumor
结局指标
主要结局
Survival rate of ICU survivors
时间窗: 3 or 6 months after ICU discharge
Critically ill patients discharged from ICU are defined as survivors
次要结局
- Assessment in depression and anxiety(3 or 6 months after ICU discharge)
- Assessment in PTSD(3 or 6 months after ICU discharge)
- Assessment in Physical dysfunction(3 or 6 months after ICU discharge)
- Assessment of life quality(3 or 6 months after ICU discharge)
- Assessment in Cognitive impairments(3 or 6 months after ICU discharge)
- Neuromuscular impairment(3 or 6 months after ICU discharge)
- Patients' care and support needs;social and economical consequences(3 or 6 months after ICU discharge)
研究者
Jian-jun Yang
Director,Department of Anesthesiology
Zhongda Hospital