Identifying Saliva Markers of Patients With Stomach, Colorectal (Including Pre-cancer Polyp) and Pancreatic Cancers
- Conditions
- Gastric CancerColorectal Cancer and Pre-cancer PolypsPancreatic Cancer
- Registration Number
- NCT01675258
- Lead Sponsor
- Hadassah Medical Organization
- Brief Summary
Colorectal cancers account for 783,000 new cases and cause 437,000 deaths per year across the world. Diagnosis in the early stages improves survival rates. Up to now, these cancers are mostly diagnosed only at later stages of the disease's course through histoimmune staining and molecular biology processes on the tissues biopsied from the gastrointestinal system under invasive diagnostic procedures of colonoscopy.
Oral fluid presents a large protein complexity and has been recently used as a diagnostic biofluid for oral, as well as systematic diseases. Using oral fluid as a bio-marker for the colorectal cancer can be advantageous as it contains gastrointestinal fluids, in addition to bacteria and bacteria lysate, which can also serve as a bio-markers' source for colorectal cancers. Proteomic technologies provide the tools needed to discover and identify disease-associated biomarkers.
The aim of the present study is to identify salivary bio-markers in patients suffering from colorectal cancers.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 150
- Has not yet started treatment for the identified cancer
- medically compromised patients
- congenital syndromes
- being treated with radiotherapy or chemotherapy.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Hadassah Medical Organization
🇮🇱Jerusalem, Israel
Hadassah Medical Organization🇮🇱Jerusalem, IsraelHadas Lemberg, PhDContact0097226777572lhadas@hadassah.org.ilMoti Moskovitz, DMD, PhDPrincipal Investigator