A study to investigate the feasibility of a mixed-method intervention to reduce salt intake and increase high-nitrate vegetable consumption in middle-aged and older Malaysian adults with elevated blood pressure

Monash University, Malaysia0 sites73 target enrollmentOctober 11, 2019

Overview

Phase: 未知
Intervention: Not specified
Conditions: Pre-hypertensive, stage 1 hypertensive or diagnosed hypertensive
Sponsor: Monash University, Malaysia
Enrollment: 73
Status: Completed
Last Updated: 4 years ago

2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32859661/ (added 19/07/2021) 2022 Results article in https://doi.org/10.3390/nu14030430 (added 20/01/2022)

Registry

who.int

Start Date

October 11, 2019

End Date

January 31, 2021

Last Updated

4 years ago

Study Type

Interventional

Sex

All

Sponsor

Monash University, Malaysia

•1\. Male and female participants with an age between 50 and 75 years from the participants of SEACO
•2\. Pre\-hypertensive, stage 1 hypertensive or diagnosed hypertensive: Any person who has a self\-reported history of hypertension (on or not on medication) or those who had a blood pressure recording of systolic blood pressure 120\-159 mmHg or diastolic blood pressure 80\-99 mmHg
•3\. Participants will have a body mass index greater than 18\.5 kg/m2
•4\. Not severely cognitively impaired (defined as a Mini Mental Examination Status \[MMSE] score of 19 or over)

•1\. Are participating in other research clinical studies
•2\. Are unable to provide consent
•3\. Adhere to any therapeutic diet such as weight loss treatments or a gluten\-free diet
•4\. Have systolic blood pressure more than or equal to 160 mmHg and /or diastolic blood pressure more than or equal to 100 mmHg
•5\. Are strictly vegan (likely to have a high intake of vegetables). Since Chinese and Indian participants are more likely to follow a vegetarian or semi\-vegetarian diet, in order to maintain representativeness across ethnic groups included in the study, only participants on strictly vegetarian diet (i.e., vegans) will be excluded from the study
•6\. Have a history of active cancer and any diagnosis of malignant cancer in the last 5 years
•7\. Have a history of excessive alcohol intake (\>21 units of alcohol per week)
•8\. Have a history of brain damage, significant head trauma (including loss of consciousness as a result)
•9\. Have a diagnosis of acute and chronic medical conditions interfering with the study outcomes such as systemic infections (tuberculosis, hepatitis B, HIV/AIDS), severe liver and kidney diseases, inflammatory bowel diseases, coronary heart diseases, cerebrovascular diseases or diabetes on insulin therapy
•10\. Have had any major surgical operations (in the past six weeks or planned in next one year) that could interfere with the study outcomes